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Single cell sequencing sheds light on why cancers form in sp
While many cells in our bodies can accumulate oncogenic mutations, the majority of these events do not lead to tumor formation as these abnormal cells are eliminated by defense mechanisms. Instead, tumors arise when a mutation happens in a p
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單細胞測序揭示了癌癥在特定細胞類型中形成的
 雖然我們體內(nèi)的許多細胞可以積累致癌突變,但這些事件中的大多數(shù)不會導(dǎo)致腫瘤形成,因為這些異常細胞被防御機制消除。相反,當突變發(fā)生在對其特異性敏感的特定細胞類型中時
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單細胞RNA測序方法的比較分析
單細胞mRNA測序(scRNA-seq)允許分析異質(zhì)細胞群,提供解決各種生物和醫(yī)學(xué)問題的令人興奮的可能性。最近開發(fā)了一系列方法,因此有必要系統(tǒng)地比較它們的靈敏度,準確度,精度和成本效
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Comparative analysis of single-cell RNA-sequencing methods
Single-cell mRNA sequencing (scRNA-seq) allows to profile heterogeneous cell populations, offering exciting possibilities to tackle a variety of biological and medical questions. A range of methods has been recently developed, making it nece
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Single-cell RNA-Seq of cells in the early human placenta may
To treat and prevent pregnancy-related disorders, researchers must understand not only what can go wrong, but when. Complications, such as preeclampsia and pre-term birth, often occur in the second or third trimester, and most research to da
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早期人胎盤中的單細胞RNA-Seq細胞可以揭示問題懷
為了治療和預(yù)防與妊娠有關(guān)的疾病,研究人員不僅要了解可能出現(xiàn)的問題,還要了解何時出錯。并發(fā)癥如先兆子癇和早產(chǎn),通常發(fā)生在妊娠中期或妊娠晚期,迄今為止的大多數(shù)研究都集
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用于高通量單細胞RNA測序的慣性有序輔助液滴微
單細胞RNA-seq揭示了細胞群中固有的細胞異質(zhì)性,這在許多臨床和研究應(yīng)用中非常重要。
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Inertial-ordering-assisted droplet microfluidics for high-th
Single-cell RNA-seq reveals the cellular heterogeneity inherent in the population of cells, which is very important in many clinical and research applications. Recent advances in droplet microfluidics have achieved the automatic isolation, l
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